Publications

• Li, S.; Lee, B.; Lao, Y.; Lertwiriyapiti, S.#; Huang, X.; and Wang, T*. Submitted. (#Undergraduate researcher)
• Andon, J. S.†; Kocher, C. D.†; Dill, K. A.*, and Wang, T*. Submitted.(†Co-first authors *Co-corresponding authors)
• Wysocki, J. W.; Wang, T. Submitted.
• Lee, B.; Mannone, J.; Wang, T. A genetically encoded selection for amyloid-β oligomer binders. Nature Chemical Biology, Accepted in principle.
  • bioRxiv preprint
• Archer, J.; Kathpalia, M.#; Lee., B.; Li, S.; Wang., T. Effects of chaperone selectivity on the assembly of plant Rubisco orthologs in E. coli. Journal of Experimental Botany, Accepted. (#Undergraduate researcher)
  • Advanced online accepted manuscript
• Yang, L.; Zhang, J.; Andon, J. S.; Li, L.; Wang, T. Rapid discovery of cyclic peptide protein aggregation inhibitors through continuous selection. Nature Chemical Biology, 2025. In press.
  • https://www.nature.com/articles/s41589-024-01823-x

• Lee, B. and Wang, T. A modular scaffold for controlling transcriptional activation via protein-protein interactions. ACS Synthetic Biology, 2022, 11, 3198.
  • https://pubs.acs.org/doi/full/10.1021/acssynbio.2c00501

• Andon, J. S.; Lee, B.; Wang, T. Enzyme directed evolution using genetically encoded biosensors. Organic & Biomolecular Chemistry, 2022, 20, 5891. (Review article)
  • https://pubs.rsc.org/en/content/articlehtml/2010/k1/d2ob00443g

Previous publications

• Miller, S. M.*, Wang, T.*, and Liu, D. R. Phage-assisted continuous and non-continuous evolution. Nature Protocols, 2020, 15, 4101. (*co-first authors)
• Miller, S. M.*, Wang, T.*, Randolph, P. B., Arbab, M., Shen, M. W., Huang, T. P., Matuszek, Z., Newby, G. A., Rees, H. A., and Liu, D. R. Continuous evolution of SpCas9 variants compatible with non-G PAMs. Nature Biotechnology, 2020, 38, 471. (*co-first authors)
• Wang, T., Badran, A. H., Huang, T. P., and Liu, D. R. Continuous Directed Evolution of Proteins with Improved Soluble Expression. Nature Chemical Biology, 2018, 14, 972.
• Galligan, J. J., Wepy, J. A., Streeter, M. D., Kingsley, P. J., Mitchener, M. M., Wauchope, O. R., Rose, K. L., Wang, T., Spiegel, D. A., and Marnett, L. J. Methylglyoxal-Derived Posttranslational Arginine Modifications are Abundant Histone Marks. Proceedings of the National Academy of Sciences, 2018, 115, 9228.
• Vastl, J. J.*, Wang, T.*, Trinh, T. B., and Spiegel, D. A. Encoded Silicon-Chip-Based Platform for Combinatorial Synthesis and Screening. ACS Combinatorial Science, 2017, 19, 255. (*co-first authors)
• Draghici, C., Wang, T., and Spiegel, D. A. Concise Total Synthesis of Glucosepane. Science, 2015, 350, 294.
• Dafre, A. L., Goldberg, J., Wang, T., Spiegel, D. A., and Maher, P. Methylglyoxal, the Foe and Friend of Glyoxalase and Trx/TrxR Systems in HT22 Nerve Cells. Free Radical Biology and Medicine, 2015, 89, 8.
• Wang, T., Streeter, M. D., and Spiegel, D. A. Generation and Characterization of Antibodies Against Arginine-Derived Advanced Glycation Endproducts. Bioorganic and Medicinal Chemistry Letters, 2015, 25, 4881.
• Wang, T., Douglass, E. F., Fitzgerald, K. J., and Spiegel, D. A. A “Turn-On” Fluorescent Sensor for Methylglyoxal. Journal of the American Chemical Society, 2013, 135, 12429.
• Wang, T., Kartika R., and Spiegel, D. A. Exploring Post-translational Arginine Modification Using Chemically Synthesized Methylglyoxal Hydroimidazolones. Journal of the American Chemical Society, 2012, 134, 8958.